Description

(-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate is a high-purity, chiral rhodium(I) complex widely recognized as a premier asymmetric hydrogenation catalyst. Its value lies in enabling the efficient and highly enantioselective synthesis of chiral intermediates, which are critical for producing optically pure pharmaceuticals and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts for complex synthetic routes.

Application

• Asymmetric Hydrogenation Catalysis: Key catalyst for the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Pharmaceutical Manufacturing: Production of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess, such as chiral amines, amino acids, and β-lactam derivatives.
• Agrochemical Synthesis: Enantioselective creation of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Synthesis of specialty flavors, fragrances, and advanced materials where optical purity is paramount.
• Academic & Industrial R&D: A valuable tool for developing new asymmetric synthetic methodologies and scaling up catalytic processes.
• Process Optimization: Used to improve the efficiency, yield, and sustainability of existing catalytic hydrogenation routes.

Basic Information

Product Name	(-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate
CAS No.	136705-77-6
Molecular Formula	C34H56F3O3P2RhS
Molecular Weight	762.70 g/mol
Synonyms	(-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)benzene(cyclooctadiene)rhodium(I) triflate; Rhodium, (1,2,5,6-η)-1,5-cyclooctadiene[(1R,1'R)-1,1'-(1,2-phenylene)bis[(2R,5R)-2,5-diethylphospholane]]-, (OC-6-33)-, trifluoromethanesulfonate; (R,R)-Et-DuPhos Rh(COD)OTf; [Rh((R,R)-Et-DuPhos)(COD)]OTf; Rhodium(I)-(R,R)-1,2-bis(2,5-diethylphospholano)benzene(1,5-cyclooctadiene) trifluoromethanesulfonate; DuPhos Rhodium Catalyst; Chiral Rhodium DuPhos Complex; Asymmetric Hydrogenation Catalyst Rh-Et-DuPhos-OTf.
EINECS	Contact for details

Quality Control

Our (-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium(I)Trifluoromethanesulfonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and elemental analysis, to verify identity, purity, and enantiomeric integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Rhodium Content	13.0 - 14.0 %
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.