Description

5-Acetyl-2,2-Difluoro-1,3-Benzodioxole is a high-purity, fluorinated benzodioxole derivative characterized by its unique acetyl-substituted structure. This compound is a valuable synthetic intermediate, prized for its ability to introduce both difluoromethylene and ketone functionalities into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its specific fluorine pattern can enhance metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly for introducing fluorinated motifs that can improve pharmacokinetic properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms can increase biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or specialty additive in the research of advanced polymers and fluorinated materials with specific optical or electronic properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex heterocyclic systems and as a versatile scaffold for further chemical modifications.
• Ligand and Catalyst Development: The acetyl and dioxole groups make it a potential precursor for creating novel chelating ligands and organocatalysts.

Basic Information

Product Name	5-Acetyl-2,2-Difluoro-1,3-Benzodioxole
CAS No.	136593-45-8
Molecular Formula	C9H6F2O3
Molecular Weight	200.14 g/mol
Synonyms	5-Acetyl-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-5-acetyl-1,3-benzodioxole; 1-(2,2-Difluoro-1,3-benzodioxol-5-yl)ethanone; 5-Acetyl-2,2-difluorobenzodioxole; 136593-45-8; Ethanone, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-
EINECS	Contact for details

Quality Control

Our production of 5-Acetyl-2,2-Difluoro-1,3-Benzodioxole adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-grade material for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.