Description

3,5-Dichloro-4-Formyl Pyridine is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the strategic positioning of its formyl and chloro substituents, enabling precise functionalization for creating complex molecular architectures. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, antiviral compounds, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the pyridine core provides bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its modifiable aromatic system.
• Cross-Coupling Reactions: The chloro groups are excellent handles for Suzuki, Stille, and Buchwald-Hartwig amination reactions to build complex biaryl and heteroaryl structures.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	3,5-Dichloro-4-Formyl Pyridine
CAS No.	136590-83-5
Molecular Formula	C6H3Cl2NO
Molecular Weight	176.00 g/mol
Synonyms	4-Pyridinecarboxaldehyde, 3,5-dichloro-; 3,5-Dichloropyridine-4-carboxaldehyde; 3,5-Dichloro-4-pyridinecarboxaldehyde; 4-Formyl-3,5-dichloropyridine; 3,5-Dichloroisonicotinaldehyde; 3,5-Dichloro-4-formylpyridine; 3,5-Dichloroisonicotinic aldehyde
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dichloro-4-Formyl Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we are compliant with relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.