Description

3-Fluoro-Dl-Alanine Methyl Ester, Hydrochloride is a fluorinated amino acid derivative, a key chiral building block in advanced organic synthesis. This compound is valued for its role in introducing fluorine atoms into peptide backbones, which can significantly alter the biological activity, metabolic stability, and physicochemical properties of target molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated peptides and peptidomimetics with enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atom can improve lipophilicity and target binding.
• Biochemical Probes: Serves as a precursor for labeled compounds used in Positron Emission Tomography (PET) imaging and other diagnostic applications.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to investigate the effect of fluorination on drug candidate potency and selectivity.
• Academic & R&D: Used in university and corporate laboratories for fundamental research in organic chemistry and fluorine chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for client projects.

Basic Information

Product Name	3-Fluoro-Dl-Alanine Methyl Ester, Hydrochloride
CAS No.	136581-47-0
Molecular Formula	C4H9FNO2 • HCl
Molecular Weight	167.58 g/mol (Free base: 121.12 g/mol)
Synonyms	DL-3-Fluoroalanine methyl ester hydrochloride; Methyl 3-fluoro-DL-alaninate hydrochloride; (±)-3-Fluoroalanine methyl ester HCl; 2-Amino-3-fluoropropionic acid methyl ester hydrochloride; Alanine, 3-fluoro-, methyl ester, hydrochloride, DL-; Methyl 2-amino-3-fluoropropanoate hydrochloride; 3-Fluoro-DL-alanine methyl ester HCl
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-Dl-Alanine Methyl Ester, Hydrochloride is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.