Description

Bromo-Peg6-Alcohol CAS NO 136399-05-8 is a bifunctional polyethylene glycol (PEG) derivative featuring a bromoalkyl group and a terminal hydroxyl group. This compound is a crucial building block in bioconjugation and pharmaceutical chemistry, enabling the precise modification of biomolecules and surfaces. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science industries for developing targeted drug delivery systems, diagnostic agents, and advanced functional polymers.

Application

• Bioconjugation Linker: Used to attach drugs, dyes, or targeting ligands to antibodies, proteins, or peptides for creating antibody-drug conjugates (ADCs) and other therapeutic constructs.
• Polymer Synthesis: Serves as a functional initiator or monomer for synthesizing amphiphilic block copolymers and PEGylated materials with tailored properties.
• Surface Functionalization: Employed to modify nanoparticles, quantum dots, or solid surfaces with PEG chains to improve biocompatibility and reduce non-specific binding.
• Crosslinking Agent: Acts as a heterobifunctional crosslinker for coupling different molecules via the reactive bromo and hydroxyl groups.
• Prodrug Development: Utilized to create cleavable PEG prodrugs, where the bromo group facilitates further functionalization for controlled drug release.
• Chemical Probe Synthesis: A key intermediate in the synthesis of fluorescent probes and molecular imaging agents for biological research.

Basic Information

Product Name	Bromo-Peg6-Alcohol
CAS No.	136399-05-8
Molecular Formula	C14H29BrO7
Molecular Weight	389.28 g/mol
Synonyms	1-Bromo-2-(2-(2-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethane; 2,5,8,11,14,17-Hexaoxanonadecan-19-ol, 1-bromo-; Br-PEG6-OH; Bromo-PEG6-alcohol; Bromo hexaethylene glycol; 1-Bromo-3,6,9,12,15,18-hexaoxaeicosan-20-ol; Bromo-terminated hexaethylene glycol monoether; α-Bromo-ω-hydroxy hexa(ethylene glycol)
EINECS	Contact for details

Quality Control

Our Bromo-Peg6-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.