Description

Ethanone, 1-(2-Bromophenyl)-2-Fluoro- (9Ci) is a specialized fluorinated and brominated aromatic ketone building block. This compound is valued for its unique molecular architecture, which facilitates the introduction of both halogen functionalities into complex organic frameworks. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with tailored electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to construct complex, multi-substituted aromatic systems.
• Chemical Biology Probe Development: Utilized as a scaffold for creating fluorescent tags or photoaffinity labels due to its halogen handles for further derivatization.

Basic Information

Product Name	Ethanone, 1-(2-Bromophenyl)-2-Fluoro- (9Ci)
CAS No.	135774-34-4
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	2'-Bromo-2-fluoroacetophenone; 1-(2-Bromophenyl)-2-fluoroethanone; 2-Fluoro-1-(2-bromophenyl)ethanone; α-Fluoro-2'-bromoacetophenone; 2-Bromophenyl 2-fluoroethyl ketone; (2-Bromophenyl)(fluoro)methanone (tautomeric form); 2-Bromo-α-fluoroacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Bromophenyl)-2-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, GC for residual solvent analysis, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.