Description

[1,1'-Biphenyl]-3-Carbonitrile, 4'-(Bromomethyl)- is a high-purity, functionalized biphenyl derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block, offering both a reactive bromomethyl group and a cyano functionality for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated biphenyl core.
• Cross-Coupling Reactions: The bromomethyl group is amenable to various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for carbon-carbon bond formation.
• Functional Polymer Monomer: Can be incorporated into polymer backbones to introduce specific chemical functionalities for advanced polymeric materials.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Carbonitrile, 4'-(Bromomethyl)-
CAS No.	135689-88-2
Molecular Formula	C14H10BrN
Molecular Weight	272.14 g/mol
Synonyms	4'-(Bromomethyl)-[1,1'-biphenyl]-3-carbonitrile; 3-Cyano-4'-(bromomethyl)biphenyl; 4'-Bromomethylbiphenyl-3-carbonitrile; Biphenyl-3-carbonitrile, 4'-(bromomethyl)-; (3-Cyanobiphenyl-4-yl)methyl bromide; 4'-(Bromomethyl)-1,1'-biphenyl-3-carbonitrile
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-3-Carbonitrile, 4'-(Bromomethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.