Description

Indoxacarb Impurity 1 is a designated reference standard used in the analytical profiling and quality control of the insecticide Indoxacarb. This compound is critical for ensuring the purity, safety, and regulatory compliance of the active pharmaceutical ingredient (API) and its formulations. It is primarily required by agrochemical manufacturers, analytical laboratories, and regulatory bodies for method development, validation, and batch release testing.

Application

• Analytical Reference Standard: Primary use as a certified reference material for HPLC, GC, and LC-MS analysis.
• Pharmaceutical Impurity Profiling: Identification and quantification of specified impurities in Indoxacarb technical material and formulated products.
• Method Development and Validation: Essential for developing and validating stability-indicating analytical methods as per ICH guidelines.
• Quality Assurance/Quality Control (QA/QC): Used in-house by manufacturers to monitor production processes and ensure batch-to-batch consistency.
• Regulatory Compliance and Submissions: Supports regulatory filings (e.g., for EPA, EU) by providing impurity identity and control strategies.
• Stability Studies: Employed to track the formation of degradation products under various stress conditions.

Basic Information

Product Name	Indoxacarb Impurity 1
CAS No.	135656-94-9
Molecular Formula	C22H17ClF3N3O7
Molecular Weight	527.84 g/mol
Synonyms	Indoxacarb Related Compound A; Methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate; (4aR)-Methyl 7-chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylate; Indoxacarb Impurity A; Indoxacarb EP Impurity A; Indoxacarb USP Impurity 1
EINECS	Contact for details

Quality Control

Every batch of Indoxacarb Impurity 1 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting standards required for reference materials. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from tests including identification, assay, and impurity profile by HPLC. We support compliance with ISO, GMP, and ICH guidelines for impurity standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Single unspecified impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.