Description

Domoic Acid CAS NO 14277-97-5 is a potent neurotoxin and excitatory amino acid produced by certain marine diatoms. It is critically important as a reference standard and analytical tool for monitoring and research in food safety and environmental toxicology. This compound is essential for laboratories in the pharmaceutical, food safety, and environmental monitoring sectors requiring precise calibration for the detection of amnesic shellfish poisoning.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the accurate quantification of domoic acid in samples via HPLC, LC-MS, or ELISA methods.
• Food Safety Testing: Calibration and quality control in the analysis of shellfish (mussels, clams, scallops), fish, and other seafood for regulatory compliance with amnesic shellfish poisoning (ASP) limits.
• Environmental Monitoring: Research and monitoring of harmful algal blooms (HABs) to study the production and environmental impact of marine biotoxins.
• Pharmacological Research: Tool compound in neuroscience research to study excitotoxicity, glutamate receptor (kainate subtype) function, and mechanisms of neurological damage.
• Diagnostic Development: Used in the development and validation of rapid test kits and immunoassays for on-site detection of marine toxins.
• Method Validation: Essential for accrediting laboratories (ISO/IEC 17025) to validate and verify analytical methods for domoic acid detection.

Basic Information

Product Name	Domoic Acid
CAS No.	14277-97-5
Molecular Formula	C15H21NO6
Molecular Weight	311.33 g/mol
Synonyms	Domoic Acid; (2S,3S,4S)-4-[(2Z,4E,6R)-6-Carboxyhepta-2,4-dien-2-yl]-3-(carboxymethyl)pyrrolidine-2-carboxylic acid; L-Domoic Acid; Amnesic Shellfish Poisoning Toxin; ASP Toxin; Isodomoic Acid A; DA; Domoate; Kainic acid analogue
EINECS	Contact for details

Quality Control

Our Domoic Acid is produced and handled under strict quality management protocols. Each batch is subjected to rigorous identity, purity, and potency testing using advanced analytical techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing batch-specific results and confirming compliance with in-house specifications suitable for use as an analytical standard. We support traceability and method validation for regulatory and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.