Description

9-N,n-Dimethylamino-9-Deoxy-10,11,12,13-Tetrahydroniddamycin is a semi-synthetic derivative of the macrolide antibiotic niddamycin, characterized by its modified amino sugar moiety. This chemical intermediate is of significant value in pharmaceutical research and development, particularly for the synthesis of novel antibacterial agents with potentially improved pharmacokinetic properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of next-generation antibiotics targeting resistant bacterial strains. The compound, identified by CAS No. 135363-57-4, is handled under controlled conditions to maintain its integrity for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic route for novel macrolide antibiotic candidates.
• Antibacterial Research: Used in structure-activity relationship (SAR) studies to develop compounds with enhanced efficacy against resistant bacteria.
• Medicinal Chemistry: Serves as a core scaffold for the modification and optimization of antibiotic properties.
• Biochemical Research: Employed in studies investigating bacterial protein synthesis inhibition mechanisms.
• Reference Standard: Can be utilized as a chromatographic or spectroscopic standard in analytical method development.

Basic Information

Product Name	9-N,n-Dimethylamino-9-Deoxy-10,11,12,13-Tetrahydroniddamycin
CAS No.	135363-57-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	9-N,N-Dimethylamino-9-deoxy-10,11,12,13-tetrahydroniddamycin; 9-Dimethylamino-9-deoxy-10,11,12,13-tetrahydroniddamycin; Tetrahydroniddamycin 9-dimethylamino-9-deoxy derivative; Niddamycin derivative, 9-dimethylamino-9-deoxy-10,11,12,13-tetrahydro-; 9-(Dimethylamino)-9-deoxy-10,11,12,13-tetrahydroniddamycin
EINECS	Contact for details

Quality Control

Our 9-N,n-Dimethylamino-9-Deoxy-10,11,12,13-Tetrahydroniddamycin is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are available upon request. We are committed to meeting the exacting standards required for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.