Description

[1R-[1α(R*),3Aβ,7Aα]]-Octahydro-δ,7A-Dimethyl-4-Oxo-1H-Indene-1-Pentanoic Acid Methyl Ester is a high-purity, complex organic ester with a defined stereochemistry, making it a critical chiral intermediate for advanced synthesis. Its precise molecular architecture provides a versatile scaffold for constructing sophisticated pharmaceutical and fine chemical targets. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients with specific stereochemical properties.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents, particularly in steroid-like or complex tricyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a precursor for high-value specialty chemicals, including fragrances, flavors, and advanced materials.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, asymmetric catalysis, and total synthesis projects.
• Process Chemistry Development: Employed in scaling up synthetic routes for commercial production, where consistent quality and stereochemical purity are paramount.

Basic Information

Product Name	[1R-[1α(R*),3Aβ,7Aα]]-Octahydro-δ,7A-Dimethyl-4-Oxo-1H-Indene-1-Pentanoic Acid Methyl Ester
CAS No.	135359-41-0
Molecular Formula	C₁₇H₂₈O₃
Molecular Weight	280.40 g/mol
Synonyms	Methyl (1R,3aS,7aR)-1-[(2R)-2-methylbutyl]octahydro-4,7a-dimethyl-1H-indene-4-carboxylate; (1R,3aS,7aR)-1-[(2R)-2-Methylbutyl]octahydro-4,7a-dimethyl-1H-indene-4-carboxylic Acid Methyl Ester; Methyl 1R,3aS,7aR-1-(2R-2-methylbutyl)octahydro-4,7a-dimethyl-1H-indene-4-carboxylate; Methyl 4,7a-dimethyl-1-[(2R)-2-methylbutyl]octahydro-1H-indene-4-carboxylate; Chiral Decalin Ester Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [1R-[1α(R*),3Aβ,7Aα]]-Octahydro-δ,7A-Dimethyl-4-Oxo-1H-Indene-1-Pentanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting standards for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.