Description

2-Bromo-6-Chloro-4-Methylaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its functionalized aromatic ring, which provides multiple reactive sites for constructing complex molecular architectures. This intermediate is particularly essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aniline motifs.
• Agrochemical Synthesis: Building block for developing herbicides, fungicides, and insecticides, leveraging its halogen substituents for bioactivity.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and organic pigments due to its amine functionality.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and liquid crystals.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating carbon-nitrogen bonds.
• Laboratory Chemical: Used in academic and industrial R&D for method development and exploratory organic synthesis.

Basic Information

Product Name	2-Bromo-6-Chloro-4-Methylaniline
CAS No.	135340-78-2
Molecular Formula	C7H7BrClN
Molecular Weight	220.49 g/mol
Synonyms	4-Amino-3-bromo-5-chlorotoluene; 3-Bromo-5-chloro-4-methylaniline; 2-Bromo-6-chloro-p-toluidine; 1-Amino-2-bromo-6-chloro-4-methylbenzene; Benzenamine, 2-bromo-6-chloro-4-methyl-; 4-Methyl-2-bromo-6-chloroaniline; (2-Bromo-6-chloro-4-methylphenyl)amine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloro-4-Methylaniline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We are committed to meeting the stringent requirements of GMP and ISO standards for intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.