Description

3',5'-Difluoropropiophenone CAS NO 135306-45-5 is a high-purity fluorinated aromatic ketone building block. This compound is valued for its role as a key intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily sought after by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in creating novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a difluorinated aromatic moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers, liquid crystals, and organic electronic materials with unique properties.
• Organic Synthesis: Employed in various name reactions and coupling chemistry to construct more complex molecular architectures in academic and industrial settings.
• Fluorine Chemistry Studies: Acts as a model compound for studying the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	3',5'-Difluoropropiophenone
CAS No.	135306-45-5
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(3,5-Difluorophenyl)-1-propanone; 3,5-Difluoropropiophenone; 3,5-Difluorophenyl Ethyl Ketone; Propiophenone, 3',5'-difluoro-; Ethyl 3,5-Difluorophenyl Ketone; 3,5-Difluoro-1-propiophenone; 3,5-Difluorophenyl Propanone
EINECS	Contact for details

Quality Control

Our 3',5'-Difluoropropiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.