Description

1-(4-Fluorophenyl)-3-(2-Hydroxyphenyl)Propane-1,3-Dione is a specialized diketone derivative featuring both fluorophenyl and hydroxyphenyl functional groups, making it a valuable intermediate for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks to develop novel materials and active pharmaceutical ingredients (APIs). It is primarily utilized in the pharmaceutical, agrochemical, and advanced material science industries for applications such as ligand synthesis and the development of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Ligand and Chelating Agent: Acts as a versatile ligand for metal complexation in catalysis and material science applications.
• Organic Electronic Materials: Investigated as a building block for organic semiconductors and light-emitting materials due to its conjugated diketone structure.
• Fluorescent Probe Development: Utilized in the design of sensitive chemical sensors and bio-imaging agents.
• Academic & Industrial Research: A fundamental reagent for methodological studies in organic chemistry and heterocycle formation.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-(2-Hydroxyphenyl)Propane-1,3-Dione
CAS No.	135276-47-0
Molecular Formula	C15H11FO3
Molecular Weight	258.25 g/mol
Synonyms	1,3-Propanedione, 1-(4-fluorophenyl)-3-(2-hydroxyphenyl)-; 2-Hydroxydibenzoylmethane, 4'-Fluoro derivative; 4'-Fluoro-2-hydroxydibenzoylmethane; 1-(4-Fluorobenzoyl)-3-(2-hydroxybenzoyl)methane; FHDM; (4-Fluorophenyl)(2-hydroxyphenyl)diketone; 2-Hydroxy-1,3-bis(4-fluorophenyl)propane-1,3-dione (common misnomer); 4-Fluoro-2'-hydroxydibenzoylmethane
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-3-(2-Hydroxyphenyl)Propane-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.