Description

2-Chloro-4-Iodobenzyl Bromide is a versatile halogenated benzyl bromide derivative, a key building block in advanced organic synthesis. Its value lies in its ability to introduce both halogen and benzyl bromide functional groups, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its halogenated structure contributes to biological activity and stability.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its reactive benzyl bromide moiety.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological systems and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Item	Detail
Product Name	2-Chloro-4-Iodobenzyl Bromide
CAS No.	135049-84-2
Molecular Formula	C7H5BrClI
Molecular Weight	331.38 g/mol
Synonyms	1-(Bromomethyl)-2-chloro-4-iodobenzene; (2-Chloro-4-iodophenyl)methyl Bromide; α-Bromo-2-chloro-4-iodotoluene; 2-Chloro-4-iodo-benzylbromide; 2-Chloro-4-iodobenzyl Bromide; Benzene, 1-(bromomethyl)-2-chloro-4-iodo-; 4-Iodo-2-chlorobenzyl Bromide
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Iodobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your R&D and scale-up activities with reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.