Description

Ethyl 2-(Dibenzylamino)-3-Hydroxypropanoate is a versatile chiral amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a protected amino group and a hydroxyl functionality, makes it a valuable intermediate for constructing complex molecules with high stereochemical purity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), chiral catalysts, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates, particularly for neurological and cardiovascular targets.
• Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis, enhancing enantioselectivity in hydrogenation and coupling reactions.
• Peptidomimetics Research: Serves as a constrained scaffold for designing and synthesizing novel peptide analogs with improved metabolic stability.
• Agrochemical Synthesis: An intermediate in the production of chiral herbicides and plant growth regulators.
• Academic & R&D Laboratories: Employed in methodological studies for developing new synthetic routes to β-amino alcohols and related compounds.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring high enantiomeric purity for electronics or material science applications.

Basic Information

Product Name	Ethyl 2-(Dibenzylamino)-3-Hydroxypropanoate
CAS No.	134936-17-7
Molecular Formula	C19H23NO3
Molecular Weight	313.39 g/mol
Synonyms	Ethyl 2-(dibenzylamino)-3-hydroxypropionate; 3-Hydroxy-2-(dibenzylamino)propionic Acid Ethyl Ester; 2-(Dibenzylamino)-3-hydroxypropionic Acid Ethyl Ester; DL-Three-2-(Dibenzylamino)-3-hydroxypropionic Acid Ethyl Ester; Ethyl 3-Hydroxy-2-(N,N-dibenzylamino)propanoate; NSC 334365; Propanoic acid, 2-(dibenzylamino)-3-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(Dibenzylamino)-3-Hydroxypropanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.