Description

1-Pyrrolidinepropanoic Acid, α-Diazo-β-Oxo-2-Thioxo-, Methyl Ester is a specialized heterocyclic building block featuring a unique diazo and thioxo functional group architecture. This compound matters as a versatile synthon for constructing complex molecular frameworks, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for applications in medicinal chemistry and novel material synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its reactive diazo moiety.
• Chemical Biology Probe: Acts as a versatile scaffold for creating photoaffinity labels or activity-based probes to study enzyme function and protein interactions.
• Material Science: Potential building block for advanced polymers or organic electronic materials requiring specific heteroatom incorporation.
• Academic & Contract Research: Employed in university and CRO laboratories for methodology development and exploring new chemical spaces in organic synthesis.

Basic Information

Product Name	1-Pyrrolidinepropanoic Acid, α-Diazo-β-Oxo-2-Thioxo-, Methyl Ester
CAS No.	134926-99-1
Molecular Formula	C9H11N3O3S
Molecular Weight	241.27 g/mol
Synonyms	Methyl 2-diazo-3-oxo-3-(2-thioxopyrrolidin-1-yl)propanoate; Methyl α-diazo-β-oxo-2-thioxo-1-pyrrolidinepropanoate; 1-Pyrrolidinepropanoic acid, α-diazo-β-oxo-2-thioxo-, methyl ester; Diazo-thioxo-pyrrolidine propanoate methyl ester; 2-Diazo-3-oxo-3-(2-thioxopyrrolidin-1-yl)propionic acid methyl ester; 1-(Methoxycarbonyl)-2-diazoacetyl-2-thioxopyrrolidine; (2-Diazo-1-methoxy-1-oxo-3-(2-thioxopyrrolidin-1-yl)propan-2-yl)oxidanium
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinepropanoic Acid, α-Diazo-β-Oxo-2-Thioxo-, Methyl Ester undergoes rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and MS for identity confirmation and purity assessment. Certificates of Analysis (COA) detailing specific lot results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); it is recommended to store under an inert gas (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.