Description

tert-Butyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize active pharmaceutical ingredients (APIs), novel chemical entities, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.
• Ligand & Catalyst Development: A valuable precursor for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	tert-Butyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate
CAS No.	134892-19-6
Molecular Formula	C₁₃H₂₅BO₄
Molecular Weight	256.15 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propanoic acid tert-butyl ester; tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate; 2-Propenoic acid, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester; tert-Butyl 3-(pinacolatoboryl)propionate; 3-(Pinacolatoboryl)propionic Acid tert-Butyl Ester; Pinacol 3-(tert-Butoxycarbonyl)ethylboronate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure high chemical purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.