Description

3-(N,n-Dimethylamino)-3-Oxopropylboronic Acid Pinacol Ester is a versatile organoboron building block, specifically a boronic ester derivative, valued for its stability and reactivity in cross-coupling reactions. This compound is essential for the efficient synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily used by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific boron-containing motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs.
• Chemical Biology Probes: Employed in the synthesis of boronic acid-based probes for sensing and protein labeling applications.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for CROs and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	3-(N,n-Dimethylamino)-3-Oxopropylboronic Acid Pinacol Ester
CAS No.	134892-18-5
Molecular Formula	C13H26BNO3
Molecular Weight	255.17 g/mol
Synonyms	3-(Dimethylamino)-3-oxopropylboronic acid pinacol ester; (3-(Dimethylamino)-3-oxopropyl)boronic acid pinacol ester; 3-(Dimethylcarbamoyl)propylboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[3-(dimethylamino)-3-oxopropyl]-1,3,2-dioxaborolane; N,N-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanamide; Propanamide, N,N-dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 3-(N,n-Dimethylamino)-3-Oxopropylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance in synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.