Description

7-Desmethylmicrocystin Lr is a key congener and metabolite of the potent cyanobacterial hepatotoxin, microcystin-LR. This compound is of significant importance for environmental monitoring, toxicological research, and the development of analytical standards and diagnostic assays. It is primarily needed by research institutions, environmental testing laboratories, and manufacturers of reference materials and immunoassay kits focused on cyanotoxin detection and water safety.

Application

• Environmental Monitoring & Water Quality Analysis: Used as a certified reference material (CRM) or analytical standard for the precise quantification of microcystin variants in freshwater samples via LC-MS/MS or HPLC.
• Toxicological & Biomedical Research: Essential for studying the metabolism, distribution, and specific toxic mechanisms of microcystins, aiding in the understanding of hepatotoxicity and potential carcinogenicity.
• Diagnostic Assay Development & Validation: Serves as a critical antigen or calibrator in the development and quality control of ELISA kits and other immunoassays for cyanotoxin detection.
• Method Development & Proficiency Testing: Employed by analytical laboratories to develop, optimize, and validate new detection methods, and as a spike-in control for inter-laboratory comparison studies.
• Regulatory Compliance & Food Safety: Supports testing for compliance with global drinking water guidelines and regulations concerning cyanotoxins in shellfish and food products.

Basic Information

Product Name	7-Desmethylmicrocystin Lr
CAS No.	134842-07-2
Molecular Formula	C48H72N10O12
Molecular Weight	981.15 g/mol
Synonyms	7-Demethylmicrocystin-LR; [D-Asp3]Microcystin-LR; Microcystin-LR (7-desmethyl); 7-Desmethyl-MCLR; (all-E)-N-Methyl-3-[(2S,3S,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoyl]-5-[(2S)-2-methyl-1-oxobutyl]-4,6-dimethyl-2-(methylamino)-3,4-dihydro-2H-pyrrole-3-carboxamide; Cyanoginosin-LA (7-desmethyl); Toxin T17 (7-desmethyl variant)
EINECS	Contact for details

Quality Control

Our 7-Desmethylmicrocystin Lr is produced and handled under strict quality protocols suitable for research and analytical applications. Each batch is characterized using advanced spectroscopic and chromatographic techniques, including NMR and High-Performance Liquid Chromatography (HPLC), to ensure high purity and structural identity. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.