Description

Butyloxycarbonyl-Cyclo(Aspartyl-Prolyl-Asparaginyl-Lysyl) Methyl Ester is a protected cyclic tetrapeptide derivative, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined intermediates for complex molecule construction. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and peptidomimetics.

Application

• Pharmaceutical Intermediate: Key precursor in the solid-phase and solution-phase synthesis of bioactive peptides and constrained peptide analogs.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates targeting various diseases.
• Peptidomimetic Development: Serves as a scaffold for creating metabolically stable peptide mimics with enhanced pharmacological properties.
• Bioconjugation Chemistry: The reactive ester and protecting groups facilitate site-specific conjugation to other molecules, carriers, or surfaces.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in cutting-edge peptide science.

Basic Information

Product Name	Butyloxycarbonyl-Cyclo(Aspartyl-Prolyl-Asparaginyl-Lysyl) Methyl Ester
CAS No.	134821-16-2
Molecular Formula	C27H43N7O11
Molecular Weight	641.68 g/mol
Synonyms	Boc-cyclo(Asp-Pro-Asn-Lys)-OMe; Boc-c(Asp-Pro-Asn-Lys)-OMe; Cyclo(L-Aspartyl-L-prolyl-L-asparaginyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysyl) Methyl Ester; N-tert-Butoxycarbonyl-cyclo(aspartyl-prolyl-asparaginyl-lysyl) Methyl Ester; Cyclic Tetrapeptide Boc-DPNK-OMe; CAS 134821-16-2
EINECS	Contact for details

Quality Control

Our Butyloxycarbonyl-Cyclo(Aspartyl-Prolyl-Asparaginyl-Lysyl) Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.