Description

(S)-2-((2-(Trifluoromethyl)Phenoxy)Methyl)Oxirane is a high-value chiral epoxide building block, distinguished by its trifluoromethylphenoxy substituent. This compound matters for its role as a critical intermediate in the synthesis of complex, biologically active molecules, where its stereochemistry and fluorine content are essential for modulating properties like metabolic stability and lipophilicity. It is needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals. The CAS number for this compound is 134598-04-2.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in academic and industrial research focused on developing new catalytic methodologies.
• Fine Chemical Building Block: Utilized in custom synthesis and contract manufacturing for producing specialty chemicals with specific stereochemical and fluorinated architectures.
• Polymer Modification: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored surface properties and chemical resistance.

Basic Information

Product Name	(S)-2-((2-(Trifluoromethyl)Phenoxy)Methyl)Oxirane
CAS No.	134598-04-2
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	(S)-2-[(2-Trifluoromethylphenoxy)methyl]oxirane; (S)-Glycidyl 2-(Trifluoromethyl)phenyl ether; (S)-1,2-Epoxy-3-((2-(trifluoromethyl)phenoxy)propane; (S)-2,3-Epoxypropyl 2-(Trifluoromethyl)phenyl ether; (S)-2-(2-Trifluoromethylphenoxymethyl)oxirane; (S)-TFMPO; (S)-Trifluoromethylphenyl glycidyl ether; (S)-α-Trifluoromethylphenoxy methyl oxirane
EINECS	Contact for details

Quality Control

Our (S)-2-((2-(Trifluoromethyl)Phenoxy)Methyl)Oxirane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reproducible results for your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its epoxide functionality and light-sensitive nature, prolonged exposure to light or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.