Description

(S)-2-((2-Nitrophenoxy)Methyl)Oxirane is a high-purity chiral epoxide building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex, optically active molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Polymer Modification: Can be used to introduce chiral nitroaryl ether functionalities into polymer chains.
• Academic & Industrial R&D: A valuable tool for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(S)-2-((2-Nitrophenoxy)Methyl)Oxirane
CAS No.	134598-03-1
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	(S)-(-)-Glycidyl 2-Nitrophenyl Ether; (S)-(-)-2,3-Epoxypropyl 2-Nitrophenyl Ether; (S)-2,3-Epoxypropyl 2-Nitrophenyl Ether; (S)-Glycidyl 2-Nitrophenyl Ether; (2S)-2-[(2-Nitrophenoxy)methyl]oxirane; (S)-(-)-1-(2-Nitrophenoxy)-2,3-epoxypropane; (S)-Epichlorohydrin 2-nitrophenyl ether derivative; Optically active glycidyl 2-nitrophenyl ether
EINECS	Contact for details

Quality Control

Our production of (S)-2-((2-Nitrophenoxy)Methyl)Oxirane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and IR for structural confirmation. Certificates of Analysis (COA) detailing purity, assay, and specific impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its epoxide functionality and light-sensitive nature, prolonged exposure to light or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.