Description

4-Piperidineacetaldehyde, 1-Acetyl--α--Methylene- is a specialized organic building block featuring a reactive aldehyde and an acetylated piperidine core. This compound matters as a versatile synthon for constructing complex nitrogen-containing heterocycles, which are pivotal in modern pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require complex amine functionalities.
• Fine Chemical Production: Serves as a precursor for creating specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry, particularly in reactions involving aldehydes and enamines.
• Chemical Biology Probes: Potential use in the design and synthesis of molecular probes for studying biological pathways and enzyme inhibition.

Basic Information

Product Name	4-Piperidineacetaldehyde, 1-Acetyl--α--Methylene-
CAS No.	134477-68-2
Molecular Formula	C10H15NO2
Molecular Weight	181.23 g/mol
Synonyms	1-Acetyl-4-(2-oxoethylidene)piperidine; 4-(2-Oxoethylidene)-1-piperidineacetic acid, 1-acetyl derivative; 1-Acetyl-α-methylenepiperidine-4-acetaldehyde; 4-(2-Oxoethylidene)piperidin-1-yl ethanone; α-Methylene-1-acetylpiperidine-4-acetaldehyde; 1-Acetyl-4-(2-oxoethylidene)piperidine; 4-(2-Oxoethylidene)-1-acetylpiperidine
EINECS	Contact for details

Quality Control

Our 4-Piperidineacetaldehyde, 1-Acetyl--α--Methylene- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.