Description

Dehydroandrographolide CAS NO 134418-28-3 is a key diterpenoid lactone compound derived from the medicinal herb *Andrographis paniculata*. This high-purity phytochemical is valued for its role as a reference standard and active pharmaceutical ingredient (API) in research and development. It is primarily sought by manufacturers and researchers in the pharmaceutical, nutraceutical, and life science sectors for its application in anti-inflammatory and hepatoprotective formulations.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and quality control of herbal extracts and finished products in pharmacopeial testing.
• Active Pharmaceutical Ingredient (API): Serves as a critical component in the formulation of herbal and modern medicines targeting liver health and inflammatory conditions.
• Nutraceutical & Dietary Supplements: Incorporated into high-end supplement formulations for its purported bioactive properties.
• Biomedical Research: Utilized in *in-vitro* and *in-vivo* studies to investigate mechanisms of action, pharmacokinetics, and therapeutic efficacy.
• Cosmeceutical Ingredients: Applied in advanced skincare products for its potential anti-inflammatory and antioxidant benefits.
• Herbal Extract Standardization: Acts as a marker compound to standardize and guarantee the potency and consistency of *Andrographis paniculata* extracts.

Basic Information

Product Name	Dehydroandrographolide
CAS No.	134418-28-3
Molecular Formula	C₂₀H₂₈O₄
Molecular Weight	332.43 g/mol
Synonyms	14-Deoxy-11,12-didehydroandrographolide; 14-Deoxy-11,12-didehydroandrographiside; Andrographolide Derivative; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone
EINECS	Contact for details

Quality Control

Our Dehydroandrographolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific pharmacopeial (e.g., USP, EP) or client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.