Description

(S)-(4-Fluorophenyl)Oxirane is a high-purity chiral epoxide building block, essential for the synthesis of enantiomerically pure compounds. Its value lies in providing a stereochemically defined fluorinated phenyl moiety, enabling precise control over molecular architecture in advanced chemical synthesis. This product is critically needed by pharmaceutical, agrochemical, and specialty chemical R&D and manufacturing teams for developing active ingredients, ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and cardiovascular drug candidates.
• Agrochemical Synthesis: Building block for creating enantiopure herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Ligand and Catalyst Preparation: Used in the synthesis of chiral ligands for asymmetric catalysis and organometallic complexes.
• Advanced Material Monomer: Serves as a precursor for epoxy resins and polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the creation of fluorinated molecular probes for studying biological systems and enzyme mechanisms.
• Flavor and Fragrance Industry: Intermediate for the synthesis of complex, high-value aroma chemicals requiring specific stereochemistry.

Basic Information

Product Name	(S)-(4-Fluorophenyl)Oxirane
CAS No.	134356-74-4
Molecular Formula	C8H7FO
Molecular Weight	138.14 g/mol
Synonyms	(S)-(-)-4-Fluorostyrene Oxide; (S)-4-Fluorophenyloxirane; (S)-1-(4-Fluorophenyl)oxirane; (2S)-2-(4-Fluorophenyl)oxirane; (S)-(-)-1,2-Epoxy-4-fluorobenzene; (S)-4-Fluorostyrene oxide; (S)-FSO; (S)-FPO
EINECS	Contact for details

Quality Control

Our (S)-(4-Fluorophenyl)Oxirane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with exacting standards for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.