Description

1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One,4-Hydroxy-4-Methyl-(9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic heterocycle class. This compound is valued for its unique structural framework, which serves as a critical building block in modern medicinal chemistry for the synthesis of complex bioactive molecules. It is primarily sought by R&D and production teams in the pharmaceutical and biotechnology sectors for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for constructing spirocyclic compounds with enhanced selectivity and metabolic stability.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Library Synthesis: Utilized in the generation of diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.

Basic Information

Product Name	1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One,4-Hydroxy-4-Methyl-(9Ci)
CAS No.	134347-95-8
Molecular Formula	C8H14N2O2
Molecular Weight	170.21 g/mol
Synonyms	4-Hydroxy-4-methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one; 4-Methyl-4-hydroxy-1-oxa-3,8-diazaspiro[4.5]decan-2-one; 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 4-hydroxy-4-methyl-; 4-Hydroxy-4-methyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one (9CI); Spiro[4.5]decan-2-one, 1-oxa-3,8-diaza-, 4-hydroxy-4-methyl-; 134347-95-8
EINECS	Contact for details

Quality Control

Our 1-Oxa-3,8-Diazaspiro[4.5]Decan-2-One,4-Hydroxy-4-Methyl-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.