Description

2-Azaspiro[4.4]Nonane is a versatile, nitrogen-containing spirocyclic organic compound with the CAS number 175-94-0. This heterocyclic building block is highly valued in advanced organic synthesis for its unique rigid, three-dimensional structure, which is crucial for modulating the physicochemical properties of target molecules. It is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, serving as a key intermediate in medicinal chemistry and drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its spirocyclic structure can enhance biological activity and environmental profile.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Employed as a linker or core component in the design of bifunctional molecules for targeted protein degradation.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Ligand Development for Catalysis: Serves as a precursor for synthesizing novel chiral ligands used in asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies and the exploration of new spirocyclic chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Azaspiro[4.4]Nonane
CAS No.	175-94-0
Molecular Formula	C8H15N
Molecular Weight	125.21 g/mol
Synonyms	2-Azaspiro[4.4]nonane; 1-Azaspiro[4.4]nonane; Azaspiro[4.4]nonane; Spiro[cyclopentane-1,2'-pyrrolidine]; 2-Aza-spiro[4.4]nonane; 2-Aza-spiro(4.4)nonane; 2-Aza-spiro-(4,4)-nonane
EINECS	205-143-8

Quality Control

Our 2-Azaspiro[4.4]Nonane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity, and impurity profiles to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.