Description

Heptamethyldisilazane is a versatile organosilicon compound widely used as a silylating agent and surface modifier. Its primary value lies in its ability to introduce trimethylsilyl (TMS) groups, effectively protecting reactive sites and altering surface properties. This makes it a critical reagent for manufacturers in the pharmaceutical, semiconductor, and specialty chemical industries. Heptamethyldisilazane CAS NO 134340-00-4 is essential for processes requiring precise control over chemical functionality and material hydrophobicity.

Application

• Pharmaceutical Intermediate Synthesis: Used as a protecting agent for hydroxyl and amino groups during the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Semiconductor Manufacturing: Employed as a surface priming agent and adhesion promoter in photolithography and for the passivation of silicon wafers.
• Gas Chromatography Derivatization: Acts as a silylating agent to improve the volatility and thermal stability of polar compounds for GC analysis.
• Polymer & Resin Modification: Imparts hydrophobic characteristics and improves compatibility when used as a surface treatment for silica fillers and other inorganic materials in composite formulations.
• Nanomaterial Functionalization: Modifies the surface chemistry of nanoparticles (e.g., silica, metal oxides) to prevent aggregation and enhance dispersion in organic matrices.
• Silicone Chemistry: Serves as a precursor or endblocking agent in the synthesis of specific silicone polymers and fluids.

Basic Information

Product Name	Heptamethyldisilazane
CAS No.	134340-00-4
Molecular Formula	C7H21NSi2
Molecular Weight	175.43 g/mol
Synonyms	1,1,1,3,3,3-Hexamethyldisilazane, HMDS; Bis(trimethylsilyl)amine; Hexamethyldisilazane; HMDS; N-(Trimethylsilyl)trimethylsilylamine; N,O-Bis(trimethylsilyl)hydroxylamine (common misnomer); 1,1,1-Trimethyl-N-(trimethylsilyl)silanamine
EINECS	Contact for details

Quality Control

Our Heptamethyldisilazane is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, containers must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.407 - 1.409
Density (20°C)	0.77 - 0.79 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.