Description

β-Oxo-Cyclobutanepropanoic Acid 1,1-Dimethylethyl Ester is a high-purity, protected β-keto ester building block of significant synthetic utility. This compound is valued for its role as a versatile intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical production. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing cyclobutane and other strained ring systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing cyclobutane rings or complex ester functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific cyclic ketone structures.
• Organic Synthesis Reagent: Serves as a precursor for Dieckmann condensation and other cyclization reactions to form complex carbocycles.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Academic & Industrial R&D: A critical reagent for methodology development and exploring new synthetic pathways in chemistry laboratories.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex aroma chemicals and musk compounds.

Basic Information

Product Name	β-Oxo-Cyclobutanepropanoic Acid 1,1-Dimethylethyl Ester
CAS No.	134302-09-3
Molecular Formula	C11H18O3
Molecular Weight	198.26 g/mol
Synonyms	tert-Butyl 3-(2-Oxocyclobutyl)propanoate; 3-(2-Oxocyclobutyl)propanoic Acid tert-Butyl Ester; 2-Oxocyclobutanepropanoic Acid tert-Butyl Ester; tert-Butyl 3-(2-Oxocyclobutyl)propionate; β-Ketocyclobutanepropionic Acid tert-Butyl Ester; 1,1-Dimethylethyl 3-(2-Oxocyclobutyl)propanoate
EINECS	Contact for details

Quality Control

Our β-Oxo-Cyclobutanepropanoic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with internal quality standards and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.