Description

1,4-Epoxy-2-Formamido-1,2,3,4-Tetrahydro-8-Trifluoromethylnaphthalene is a high-purity, advanced pharmaceutical intermediate characterized by its unique naphthalene backbone with epoxy and trifluoromethyl functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a precursor for developing novel pesticides and herbicides, leveraging the bioactivity of the trifluoromethyl group.
• Organic Synthesis: Used in academic and industrial R&D for constructing polycyclic frameworks and studying epoxy ring-opening reactions.
• Fluorine Chemistry: An important substrate for investigating the influence of fluorine atoms on molecular properties in medicinal chemistry.
• Material Science Precursor: Potential use in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.

Basic Information

Product Name	1,4-Epoxy-2-Formamido-1,2,3,4-Tetrahydro-8-Trifluoromethylnaphthalene
CAS No.	134254-12-9
Molecular Formula	C₁₃H₁₁F₃N₂O₂
Molecular Weight	284.24 g/mol
Synonyms	8-(Trifluoromethyl)-1,4-epoxy-2-formamido-1,2,3,4-tetrahydronaphthalene; 1,2,3,4-Tetrahydro-8-(trifluoromethyl)-1,4-epoxy-2-naphthalenecarboxamide; 1,4-Epoxy-2-formamido-1,2,3,4-tetrahydro-8-(trifluoromethyl)naphthalene; 134254-12-9; 8-Trifluoromethyl-1,4-epoxy-2-formamido-1,2,3,4-tetrahydronaphthalene
EINECS	Contact for details

Quality Control

Our 1,4-Epoxy-2-Formamido-1,2,3,4-Tetrahydro-8-Trifluoromethylnaphthalene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.