Description

Cyclobutanecarboxylic Acid, 3-Ethylidene-2-Methyl-, Methyl Ester, [1R- is a high-purity, chiral cyclobutane derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique strained-ring structure and stereochemistry, which are essential for constructing complex molecular architectures with specific biological activity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for creating molecules with specific three-dimensional configurations.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclobutane ring contributes to unique biological activity and stability.
• Fine Chemical Production: Serves as a specialized precursor for synthesizing flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: Employed in methodological studies and process chemistry for developing new synthetic routes involving strained ring systems.
• Material Science Precursor: Potential use in the synthesis of monomers or ligands for advanced polymeric or coordination compounds.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-Ethylidene-2-Methyl-, Methyl Ester, [1R-
CAS No.	134235-12-4
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R)-3-Ethylidene-2-methylcyclobutanecarboxylic acid methyl ester; Methyl (1R)-3-ethylidene-2-methylcyclobutanecarboxylate; (R)-Methyl 3-ethylidene-2-methylcyclobutanecarboxylate; 3-Ethylidene-2-methyl-cyclobutanecarboxylic acid methyl ester, (1R)-; [1R-(1α)]-3-Ethylidene-2-methylcyclobutanecarboxylic Acid Methyl Ester; Cyclobutane carboxylic acid, 3-ethylidene-2-methyl-, methyl ester, (1R)-; Methyl (R)-3-ethylidene-2-methylcyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarboxylic Acid, 3-Ethylidene-2-Methyl-, Methyl Ester, [1R- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques, with comprehensive Certificates of Analysis (COA) provided to verify identity, purity, and chiral integrity. We support cGMP and ISO compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.