Description

9-Deoxo-12-Deoxy-9,12-Epoxyerythromycin is a semi-synthetic derivative of the macrolide antibiotic erythromycin, representing a key intermediate in the synthesis of advanced antibiotic compounds. This compound is valued for its structural modifications, which are engineered to enhance stability, bioavailability, and target specificity in pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel antibacterial agents and the study of macrolide structure-activity relationships.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation macrolide antibiotics with improved pharmacological profiles.
• Antibacterial Research: Used in microbiological and biochemical research to investigate mechanisms of action and resistance against bacterial pathogens.
• Medicinal Chemistry: Serves as a scaffold for the design and development of new chemical entities targeting bacterial protein synthesis.
• Process Development: Employed in scaling up and optimizing synthetic routes for the commercial production of advanced erythromycin derivatives.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	9-Deoxo-12-Deoxy-9,12-Epoxyerythromycin
CAS No.	134108-11-5
Molecular Formula	C37H67NO12
Molecular Weight	717.93 g/mol
Synonyms	9-Deoxo-9,12-epoxyerythromycin; 9-Deoxo-12-deoxy-9,12-epoxyerythromycin; Erythromycin 9,12-epoxide derivative; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our 9-Deoxo-12-Deoxy-9,12-Epoxyerythromycin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent controls for residual solvents and related substances. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Long-term storage under inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.