Description

2,2-Difluoro-1-Phenyl-Butane-1,3-Dione is a specialized fluorinated diketone compound, serving as a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both a phenyl group and reactive difluoro-substituted diketone moiety, makes it a critical precursor for synthesizing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries who require precise fluorination to modulate bioactivity, stability, and material characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, improving their efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for β-diketone ligands used in coordination chemistry and catalysis, particularly for metal complexes.
• Advanced Material Research: Employed in the development of fluorinated polymers and organic electronic materials to fine-tune optical and electronic properties.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and creating libraries of novel fluorinated compounds for screening.

Basic Information

Product Name	2,2-Difluoro-1-Phenyl-Butane-1,3-Dione
CAS No.	133860-73-8
Molecular Formula	C10H8F2O2
Molecular Weight	198.17 g/mol
Synonyms	1-Phenyl-2,2-difluorobutane-1,3-dione; 2,2-Difluoro-1-phenyl-1,3-butanedione; Difluorobenzoylacetone; α,α-Difluorobenzoylacetone; 4,4-Difluoro-1-phenyl-1,3-butanedione; 2,2-Difluoro-4-phenyl-3-oxobutanal (tautomer); DFB; 133860-73-8
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-1-Phenyl-Butane-1,3-Dione is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by techniques including HPLC, GC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.