Description

Cyclobutanecarboxaldehyde, 2-(1-Methoxyethyl)-, [1S-[1Alpha,2Alpha(R*)]]- (9Ci) is a chiral, high-purity chemical building block of significant interest in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which make it a critical precursor for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the creation of advanced, stereochemically-defined pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereocenters.
• Academic & Institutional R&D: Utilized in university and government laboratories for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	Cyclobutanecarboxaldehyde, 2-(1-Methoxyethyl)-, [1S-[1Alpha,2Alpha(R*)]]- (9Ci)
CAS No.	133796-83-5
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	(1S,2S)-2-[(1R)-1-Methoxyethyl]cyclobutanecarboxaldehyde; (1S,2S)-2-[(R)-1-Methoxyethyl]cyclobutanecarbaldehyde; [1S-(1α,2α(R*))]-2-(1-Methoxyethyl)cyclobutanecarboxaldehyde; (1S,2S)-2-(1-Methoxyethyl)cyclobutanecarbaldehyde (relative stereochemistry); Chiral Cyclobutane Aldehyde Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this chiral aldehyde adheres to strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity, which is critical for its application in asymmetric synthesis. Quality is verified through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity, the container should be kept tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.