Description

Methyl 1-(4-Fluorophenyl)-5-Oxopyrrolidine-3-Carboxylate is a high-purity organic intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought after by R&D laboratories, process chemists, and manufacturers in the pharmaceutical and agrochemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated pyrrolidinone structure for bioactivity.
• Chemical Synthesis Building Block: Employed in organic chemistry research for constructing γ-lactam (pyrrolidinone) frameworks, which are prevalent in many natural products and medicinal compounds.
• Material Science Research: Investigated as a monomer or specialty additive for creating polymers with specific thermal or optical properties.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for use in multi-step, kilogram-scale production of target molecules for clients.

Basic Information

Product Name	Methyl 1-(4-Fluorophenyl)-5-Oxopyrrolidine-3-Carboxylate
CAS No.	133747-62-3
Molecular Formula	C12H12FNO3
Molecular Weight	237.23 g/mol
Synonyms	Methyl 1-(4-fluorophenyl)-5-oxo-3-pyrrolidinecarboxylate; 1-(4-Fluorophenyl)-5-oxopyrrolidine-3-carboxylic acid methyl ester; 3-Carbomethoxy-1-(4-fluorophenyl)-2-pyrrolidinone; Methyl 1-(p-fluorophenyl)-5-oxo-3-pyrrolidinecarboxylate; 1-(4-Fluorophenyl)-5-oxo-3-pyrrolidinecarboxylic acid methyl ester; 4-Fluoro-1-(5-oxo-3-pyrrolidinyl)benzoic acid methyl ester (tautomeric form); 133747-62-3
EINECS	Contact for details

Quality Control

Our Methyl 1-(4-Fluorophenyl)-5-Oxopyrrolidine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.