Description

Cyclopropane, 2-Butoxy-1,1-Difluoro- (9Ci) is a specialized fluorinated cyclopropane derivative, a class of compounds valued for their unique reactivity and physicochemical properties. This compound matters as a versatile building block in advanced organic synthesis, particularly for introducing the difluorocyclopropane moiety into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially those requiring fluorinated cyclopropane rings for metabolic stability or bioavailability enhancement.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the difluorocyclopropane structure can contribute to biological activity and environmental persistence profiles.
• Material Science Research: Investigated as a monomer or precursor for developing novel fluorinated polymers with potential applications in coatings, electronics, or specialty materials.
• Organic Synthesis Building Block: Employed in [3+2] cycloadditions, ring-opening reactions, and other transformations to construct complex, fluorinated molecular architectures in academic and industrial laboratories.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel fluorinated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	Cyclopropane, 2-Butoxy-1,1-Difluoro- (9Ci)
CAS No.	133744-89-5
Molecular Formula	C9H16F2O
Molecular Weight	178.22 g/mol
Synonyms	2-Butoxy-1,1-difluorocyclopropane; 1,1-Difluoro-2-butoxycyclopropane; Difluoro(butoxymethylene)cyclopropane; (Butoxydifluoromethyl)cyclopropane; 2-Butoxy-1,1-difluoro-cyclopropane; NSC 406915; Cyclopropane, difluoro(butoxymethylene)-
EINECS	Contact for details

Quality Control

Every batch of Cyclopropane, 2-Butoxy-1,1-Difluoro- (9Ci) is produced and analyzed under strict quality management protocols. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including GC, GC-MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent evaporation and potential moisture ingress. Store away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.