Description

1-(2-Chlorophenyl)-2-Hydroxyethanone is a versatile aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the production of complex pharmaceutical molecules and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of chiral drugs, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its chlorophenyl moiety for biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty dyes, pigments, and performance chemicals.
• Academic and R&D: A valuable compound for methodological research in organic chemistry, including studies on ketone reduction and asymmetric synthesis.
• Material Science: Investigated as a monomer or additive in the development of specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	1-(2-Chlorophenyl)-2-Hydroxyethanone
CAS No.	133662-20-1
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	2-Chlorophenacyl Alcohol; 2'-Chloro-2-hydroxyacetophenone; α-Hydroxy-2'-chloroacetophenone; 1-(2-Chlorophenyl)-2-hydroxyethan-1-one; 2-Hydroxy-1-(2-chlorophenyl)ethanone; (2-Chlorophenyl)(hydroxy)methanone; o-Chlorophenacyl Alcohol
EINECS	Contact for details

Quality Control

Our 1-(2-Chlorophenyl)-2-Hydroxyethanone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, chiral purity (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Optical Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.