Description

1-(Bromomethyl)-3-Methoxy-2-Nitrobenzene is a versatile and high-purity aromatic building block, essential for advanced organic synthesis. Its unique structure, featuring bromomethyl, methoxy, and nitro functional groups, makes it a critical intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific aromatic substitution patterns.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the nitro and bromomethyl groups facilitate further functionalization.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, or organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex organic dyes and pigments due to its nitro-aromatic core.
• Cross-Coupling Reactions: The bromomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	1-(Bromomethyl)-3-Methoxy-2-Nitrobenzene
CAS No.	133486-62-1
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	2-Nitro-3-methoxybenzyl bromide; 3-Methoxy-2-nitrobenzyl bromide; (3-Methoxy-2-nitrophenyl)methyl bromide; 2-Nitro-m-anisyl bromide; α-Bromo-3-methoxy-2-nitrotoluene; 1-Bromomethyl-3-methoxy-2-nitrobenzene; Benzene, 1-(bromomethyl)-3-methoxy-2-nitro-
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-3-Methoxy-2-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.