Description

4-Bromobenzeneboronic Acid n-Methyldiethanolamine Ester is a specialized organoboron compound, valued for its enhanced stability and solubility profile compared to its free boronic acid counterpart. This derivative is a crucial intermediate in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for the efficient construction of complex biaryl structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific halogenated aromatic frameworks.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and protein interactions.
• Cross-Coupling Reactions: Primarily functions as a stable, soluble boronate ester reagent in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds.

Basic Information

Item	Detail
Product Name	4-Bromobenzeneboronic Acid n-Methyldiethanolamine Ester
CAS No.	133468-58-3
Molecular Formula	C11H17BBrNO2
Molecular Weight	286.97 g/mol
Synonyms	4-Bromophenylboronic Acid N-Methyldiethanolamine Ester; B-(4-Bromophenyl)-N-methyldiethanolamine Boronate; 4-Bromobenzene-1-boronic Acid - N-Methyldiethanolamine (1:1); N-Methyldiethanolamine 4-Bromobenzeneboronate; 4-Bromobenzene-1-boronic Acid MDEA Ester; 4-Bromophenylboronic Acid MDEA Ester; (4-Bromophenyl)boronic Acid N-Methyldiethanolamine Ester
EINECS	Contact for details

Quality Control

Our 4-Bromobenzeneboronic Acid n-Methyldiethanolamine Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.