Description

2-p-Tolyl-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid is a high-value, heterocyclic carboxylic acid derivative serving as a critical building block in advanced organic synthesis. Its imidazopyridine core fused with a tolyl group makes it a versatile intermediate for constructing complex molecular architectures with targeted biological activity. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS), inflammation, or infectious diseases.
• Agrochemical Research: Used as a scaffold for developing new herbicides, fungicides, or insecticides with improved efficacy and selectivity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, organic semiconductors, or light-emitting materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of diagnostic tools.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Catalyst & Ligand Development: Potential building block for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2-p-Tolyl-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid
CAS No.	133427-26-6
Molecular Formula	C15H12N2O2
Molecular Weight	252.27 g/mol
Synonyms	2-(4-Methylphenyl)imidazo[1,2-a]pyridine-8-carboxylic acid; 2-(p-Tolyl)imidazo[1,2-a]pyridine-8-carboxylic acid; 8-Carboxy-2-p-tolylimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-8-carboxylic acid, 2-(4-methylphenyl)-; 2-(4-Methylphenyl)-imidazo[1,2-a]pyridine-8-carboxylic acid; 133427-26-6; 2-p-Tolylimidazo[1,2-a]pyridine-8-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-p-Tolyl-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.