Description

(R)-3-[4-(2-Methoxyethyl)Phenoxy]-1,2-Epoxypropane is a high-purity chiral epoxide building block of significant importance in advanced organic synthesis. Its defined stereochemistry and reactive oxirane ring make it a critical intermediate for constructing complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty materials where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers, adrenergic agents, and other cardiovascular or neurological drugs.
• Asymmetric Synthesis: Used in the preparation of enantiomerically pure compounds via nucleophilic ring-opening reactions of the epoxide.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis.
• Material Science Research: Building block for novel polymers or dendrimers with specific optical or mechanical properties.
• Agrochemical Synthesis: Intermediate in the production of certain chiral herbicides or plant growth regulators.
• Academic & R&D: Valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-3-[4-(2-Methoxyethyl)Phenoxy]-1,2-Epoxypropane
CAS No.	133397-54-3
Molecular Formula	C₁₂H₁₆O₃
Molecular Weight	208.25 g/mol
Synonyms	(R)-1,2-Epoxy-3-[4-(2-methoxyethoxy)phenoxy]propane; (R)-Glycidyl 4-(2-Methoxyethyl)phenyl Ether; (R)-4-(2-Methoxyethyl)phenyl Glycidyl Ether; (R)-3-[p-(2-Methoxyethyl)phenoxy]-1,2-epoxypropane; (R)-EGMPE; (R)-Epoxide of 4-(2-Methoxyethyl)phenol; (R)-Methoxyethyl Phenoxy Glycidyl Ether; (2R)-2-[(4-(2-Methoxyethyl)phenoxy)methyl]oxirane
EINECS	Contact for details

Quality Control

Our (R)-3-[4-(2-Methoxyethyl)Phenoxy]-1,2-Epoxypropane is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity and purity. Certificates of Analysis (COA) detailing specific parameters such as assay, enantiomeric excess, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.