Description

1-(4-Aminobenzyl)-Dtpa is a bifunctional chelating agent and a derivative of diethylenetriaminepentaacetic acid (DTPA). This compound is valued for its ability to form stable complexes with a wide range of metal ions, particularly lanthanides and actinides. It is primarily utilized in the development of advanced radiopharmaceuticals, diagnostic imaging agents, and specialized chemical research. The product is supplied under strict quality control to ensure reliability for sensitive applications.

Application

• Radiopharmaceutical Precursor: A key intermediate for synthesizing metal chelates used in Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT) imaging agents.
• Diagnostic Chelation: Used to create stable complexes with radioisotopes like Gadolinium (Gd³⁺) for Magnetic Resonance Imaging (MRI) contrast agents.
• Therapeutic Agent Development: Serves as a building block for targeted alpha therapy (TAT) and radioimmunotherapy (RIT) conjugates.
• Chemical Research: Employed in academic and industrial research for studying metal-ligand interactions, coordination chemistry, and novel chelator synthesis.
• Analytical Chemistry: Can be used as a complexing agent in trace metal analysis and separation techniques.

Basic Information

Product Name	1-(4-Aminobenzyl)-Dtpa
CAS No.	133097-22-0
Molecular Formula	C16H23N3O10
Molecular Weight	417.37 g/mol
Synonyms	1-(4-Aminobenzyl)diethylenetriaminepentaacetic Acid; p-Aminobenzyl-DTPA; 4-Aminobenzyl-DTPA; ABZ-DTPA; 2-[Bis[2-[bis(carboxymethyl)amino]ethyl]amino]-2-(4-aminophenyl)acetic Acid; (4-Aminophenyl)methyldiethylenetriaminepentaacetic Acid; DTPA-ABn; DTPA-p-Aminobenzyl Ester
EINECS	Contact for details

Quality Control

Our 1-(4-Aminobenzyl)-Dtpa is manufactured under a quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency suitable for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.