Description

trans-2-(3,4-Difluorophenyl)-5-(trans-4-n-Pentylcyclohexyl)-1,3-Dioxane is a high-purity, advanced organic intermediate characterized by its unique dioxane ring structure with fluorinated aromatic and cyclohexyl substituents. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering precise stereochemistry and functional group compatibility. It is primarily needed by research and development teams in the pharmaceutical and advanced materials sectors, particularly for creating novel liquid crystal compounds and active pharmaceutical ingredients (APIs) where specific molecular geometry is essential.

Application

• Liquid Crystal (LC) Material Synthesis: A key chiral intermediate for the development of ferroelectric and nematic liquid crystals used in high-performance displays (LCDs).
• Pharmaceutical Intermediate: Serves as a sophisticated building block in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system.
• Advanced Organic Electronics: Used in research for developing organic semiconductors and charge-transport materials due to its stable, rigid core structure.
• Chiral Catalyst & Ligand Precursor: The defined stereocenters make it a valuable starting point for synthesizing chiral auxiliaries and ligands for asymmetric catalysis.
• Fluorinated Compound Research: The difluorophenyl group provides a metabolically stable motif, making it relevant for agrochemical and medicinal chemistry research programs.
• Material Science Additive: Investigated for use in polymer modification to enhance thermal stability and optical properties.

Basic Information

Product Name	trans-2-(3,4-Difluorophenyl)-5-(trans-4-n-Pentylcyclohexyl)-1,3-Dioxane
CAS No.	133059-04-8
Molecular Formula	C21H30F2O2
Molecular Weight	352.46 g/mol
Synonyms	trans-2-(3,4-Difluorophenyl)-5-(trans-4-pentylcyclohexyl)-1,3-dioxane; 1,3-Dioxane, 2-(3,4-difluorophenyl)-5-[trans-4-(pentyl)cyclohexyl]-, trans-; 5-(trans-4-Pentylcyclohexyl)-2-(3,4-difluorophenyl)-1,3-dioxane; 2-(3,4-Difluorophenyl)-5-(trans-4-pentylcyclohexyl)-1,3-dioxane; Difluorophenyl Pentylcyclohexyl Dioxane; FLC Intermediate 133059-04-8; CAS 133059-04-8
EINECS	Contact for details

Quality Control

Our trans-2-(3,4-Difluorophenyl)-5-(trans-4-n-Pentylcyclohexyl)-1,3-Dioxane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, precise stereochemical integrity, and consistent lot-to-lot performance. Standard quality checks include chiral purity verification and control of key organic impurities. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), enantiomeric excess, and residual solvents are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.