Description

trans-2-(4-Fluorophenyl)-5-(trans-4-n-Propylcyclohexyl)-1,3-Dioxane is a high-purity, advanced organic intermediate with a specific stereochemical configuration. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in the pharmaceutical and advanced materials sectors. It is essential for researchers and manufacturers developing novel liquid crystal materials, active pharmaceutical ingredients (APIs), and other specialty chemicals where precise molecular architecture is required.

Application

• Liquid Crystal (LC) Material Synthesis: A key chiral dopant or intermediate for ferroelectric and nematic liquid crystal mixtures used in high-performance displays (LCDs).
• Pharmaceutical Intermediate: Serves as a sophisticated building block in the multi-step synthesis of complex drug candidates, especially those targeting the central nervous system.
• Advanced Organic Electronics: Used in the research and development of organic semiconductors and light-emitting materials due to its stable, rigid structure.
• Chiral Catalyst/ Ligand Precursor: The defined stereochemistry makes it a valuable starting point for synthesizing chiral ligands used in asymmetric catalysis.
• Specialty Polymer Additive: Imparts specific optical or structural properties when incorporated into high-performance polymer matrices.
• Chemical Research & Development: A valuable reference standard and reagent for academic and industrial R&D in synthetic organic chemistry.

Basic Information

Product Name	trans-2-(4-Fluorophenyl)-5-(trans-4-n-Propylcyclohexyl)-1,3-Dioxane
CAS No.	133058-92-1
Molecular Formula	C19H27FO2
Molecular Weight	306.42 g/mol
Synonyms	4'-(trans-4-Propylcyclohexyl)-2-fluoro-1,3-dioxane; 2-(4-Fluorophenyl)-5-(trans-4-propylcyclohexyl)-1,3-dioxane; 1,3-Dioxane, 2-(4-fluorophenyl)-5-[4-(propyl)cyclohexyl]-, trans-; trans-2-(p-Fluorophenyl)-5-(trans-4-propylcyclohexyl)-1,3-dioxane; 4-(trans-4-Propylcyclohexyl)-2-(4-fluorophenyl)-1,3-dioxane; FPPD; Liquid Crystal Intermediate 133058-92-1
EINECS	Contact for details

Quality Control

Our trans-2-(4-Fluorophenyl)-5-(trans-4-n-Propylcyclohexyl)-1,3-Dioxane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting customer specifications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥98.0% by HPLC), and impurity profile is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorinating agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (trans,trans isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.