Description

3-(4-Fluorophenyl)-1-(2-Hydroxyphenyl)Prop-2-En-1-One is a specialized chalcone derivative, a key structural motif in organic and medicinal chemistry. This compound matters as a versatile synthetic intermediate and building block for developing novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation and metabolic disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its bioactive chalcone scaffold.
• Organic Synthesis: Serves as a key precursor for synthesizing more complex heterocyclic compounds like flavones and aurones.
• Material Science: Investigated for its potential in creating organic semiconductors and non-linear optical (NLO) materials due to its conjugated system.
• Biochemical Research: Employed in academic and industrial R&D as a reference standard or probe molecule for studying biological pathways.
• Flavonoid Analog Synthesis: Used to create synthetic analogs of natural flavonoids for enhanced bioavailability and activity studies.

Basic Information

Product Name	3-(4-Fluorophenyl)-1-(2-Hydroxyphenyl)Prop-2-En-1-One
CAS No.	132971-92-7
Molecular Formula	C15H11FO2
Molecular Weight	242.25 g/mol
Synonyms	2'-Hydroxy-4'-fluorochalcone; 1-(2-Hydroxyphenyl)-3-(4-fluorophenyl)-2-propen-1-one; 4-Fluoro-2'-hydroxychalcone; (E)-3-(4-Fluorophenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one; 3-(4-Fluorophenyl)-1-(2-hydroxyphenyl)-2-propen-1-one; NSC 407303; 4-Fluorochalcone derivative
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-1-(2-Hydroxyphenyl)Prop-2-En-1-One is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.