Description

Cyclopropanecarboxaldehyde, 1-[(1,1-Dimethylethyl)Thio]- (9Ci) is a specialized organosulfur building block featuring a cyclopropane ring and a tert-butylthio protecting group. This compound matters as a high-value intermediate for the synthesis of complex molecules, particularly in pharmaceutical research where the cyclopropane moiety is prized for its ability to modulate biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the bioactivity of the cyclopropane scaffold.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and transition metal complexes.
• Advanced Material Precursor: A starting material for synthesizing monomers or additives that impart unique properties to polymers and functional coatings.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 1-[(1,1-Dimethylethyl)Thio]- (9Ci)
CAS No.	132866-22-9
Molecular Formula	C9H16OS
Molecular Weight	172.29 g/mol
Synonyms	1-(tert-Butylthio)cyclopropanecarboxaldehyde; 1-[(1,1-Dimethylethyl)thio]cyclopropanecarbaldehyde; 1-(tert-Butylsulfanyl)cyclopropanecarbaldehyde; Cyclopropanecarboxaldehyde, 1-[(1,1-dimethylethyl)thio]-; 1-(tert-Butylthio)cyclopropanecarbaldehyde; tert-Butylthiocyclopropanecarboxaldehyde; 1-(tert-Butylmercapto)cyclopropanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 1-[(1,1-Dimethylethyl)Thio]- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, minimize headspace and exposure to air after opening. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.