Description

Ethanone, 1-(3,5-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci) is a high-purity trifluoromethyl ketone derivative, a key building block in advanced organic synthesis. Its unique structure, featuring a trifluoroacetyl group attached to a dimethylphenyl ring, makes it a versatile intermediate for introducing fluorinated motifs, which are critical for modulating the physicochemical properties of target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a key fluorinated building block for electronic chemicals used in display and lighting technologies.
• Advanced Polymer Modification: Employed to introduce fluorine into polymer chains, enhancing material properties like chemical resistance, thermal stability, and low surface energy for coatings.
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions and as a substrate for developing novel fluorination methodologies in academic and industrial research.

Basic Information

Product Name	Ethanone, 1-(3,5-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	132719-10-9
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	1-(3,5-Dimethylphenyl)-2,2,2-trifluoroethanone; 3',5'-Dimethyl-2,2,2-trifluoroacetophenone; 2,2,2-Trifluoro-1-(3,5-dimethylphenyl)ethanone; 3,5-Dimethyl-α,α,α-trifluoroacetophenone; α,α,α-Trifluoro-3',5'-dimethylacetophenone; TFAP derivative; Trifluoromethyl ketone intermediate
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3,5-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent batch-to-batch performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.