Description

6-Cyano-3,4-Dihydro-2,2-Dimethyl-2H-1-Benzopyran is a high-purity, versatile chromane derivative organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its functionalized benzopyran scaffold, which serves as a critical building block for the development of complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working in the fine chemical, pharmaceutical, and crop protection industries, where it is used to construct novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and cardiovascular diseases.
• Agrochemical Synthesis: Building block for developing advanced pesticides, herbicides, and fungicides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymeric materials due to its rigid, functionalized structure.
• Flavor & Fragrance Chemistry: Intermediate for synthesizing complex aroma chemicals and flavoring agents with specific olfactory properties.
• Academic & Industrial R&D: Serves as a standard reagent in methodological studies for novel cyclization and functionalization reactions in organic chemistry.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and optical brighteners where the chromane core contributes to color and stability.

Basic Information

Product Name	6-Cyano-3,4-Dihydro-2,2-Dimethyl-2H-1-Benzopyran
CAS No.	132685-98-4
Molecular Formula	C₁₂H₁₃NO
Molecular Weight	187.24 g/mol
Synonyms	2,2-Dimethyl-6-cyanochroman; 6-Cyano-2,2-dimethylchroman; 2,2-Dimethyl-6-cyano-3,4-dihydro-2H-1-benzopyran; 2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-2,2-dimethyl-; 132685-98-4; 6-Cyano-2,2-dimethyl-3,4-dihydro-2H-chromene
EINECS	Contact for details

Quality Control

Our production of 6-Cyano-3,4-Dihydro-2,2-Dimethyl-2H-1-Benzopyran adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality system aligned with cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to direct light should be avoided. For long-term storage (>12 months), consider storage under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.