Description

tert-Butyl 6-oxo-1-azaspiro[4.4]nonane-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic lactam structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compounds in drug discovery programs.
• Protease Inhibitor Development: The lactam moiety makes it valuable for research into inhibitors targeting specific enzymes.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and novel compound library generation.

Basic Information

Product Name	tert-Butyl 6-oxo-1-azaspiro[4.4]nonane-1-carboxylate
CAS No.	132564-22-8
Molecular Formula	C₁₃H₂₁NO₃
Molecular Weight	239.31 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-6-oxo-1-azaspiro[4.4]nonane; 1-Boc-6-oxo-1-azaspiro[4.4]nonane; tert-Butyl 6-oxo-1-azaspiro[4.4]nonane-1-carboxylate; 6-Oxo-1-azaspiro[4.4]nonane-1-carboxylic acid tert-butyl ester; 1-Azaspiro[4.4]nonane-1-carboxylic acid, 6-oxo-, 1,1-dimethylethyl ester; Boc-6-oxo-1-azaspiro[4.4]nonane; 132564-22-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-oxo-1-azaspiro[4.4]nonane-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.